NIH COMPOUND SUMMARY on Carfentanil most potent opioids known

Shouldn't They Be working like they do on cancer treatments not off on studies while pain patients are being denied their life enabling medications.
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NIH COMPOUND SUMMARY on Carfentanil most potent opioids known

Post by admin » Wed Mar 27, 2019 12:07 pm

  • Carfentanyl is a monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of methyl 4-anilino-1-(2-phenylethyl)piperidine-4-carboxylate with propanoic acid. It has a role as a mu-opioid receptor agonist, an opioid analgesic and a tranquilizing drug. It is a member of piperidines, a methyl ester, a tertiary amino compound and a tertiary carboxamide.
SOURCE: Click Here below
https://pubchem.ncbi.nlm.nih.gov/compou ... ection=Top

Source: ChEBI
Record Name: Carfentanyl
SOURCE URL: http://www.ebi.ac.uk/chebi/searchId.do? ... HEBI:61084
  • Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially). Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 microgram. It is marketed under the trade name Wildnil as a general anaesthetic agent for large animals. Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans. Currently sufentanil, approximately 10–20 times less potent (500 to 1000 times the efficacy of morphine per weight) than carfentanil, is the maximum strength fentanyl analog for use in humans.
Source: DrugBank
Record Name: Carfentanil
Description: Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known
URL: http://www.drugbank.ca/drugs/DB01535

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